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| Registros recuperados: 11 | |
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| Canhas, Isabela Nascimento; Heneine, Luiz Guilherme Dias; Fraga, Thaís; Assis, Débora Cristina Sampaio de; Borges, Márcia Helena; Chartone-Souza, Edmar; Nascimento, Andréa Maria Amaral. |
| Toxins and venoms produced by living organisms have exhibited a variety of biological activities against microorganisms. In this study, we tested seven snake venoms from the family Viperidae for antibacterial activity and the activities of reversal of antibiotic resistance and inhibition of biofilm formation against 22 clinical isolates of Staphylococcus aureus. Bothrops moojeni venom exhibited anti staphylococcal activity with the lowest mean value of minimum inhibitory concentration (MIC). Moreover, reversal of antibiotic resistance was observed for combinations of B. moojeni venom (½ x MIC) and norfloxacin or ampicillin (both ½ x MIC) for 86.4% and 50% of the isolates, respectively. B. moojeni venom alone at ½ MIC inhibited 90% of biofilm formation,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops moojeni; Bacteria; Antibiotic-resistance; NorA efflux pump; Biofilm.. |
| Ano: 2017 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/33826 |
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| Rabelo,R.C.; Melo,M.M.; Silva Júnior,P.G.; Lúcia,M.. |
| Estabeleceram-se a pressão venosa periférica (PVP), a pressão venosa central (PVC), a pressão arterial invasiva (PAI) e a pressão arterial não invasiva (PANI) em cães após diferentes eventos de hipotensão. Foram utilizados 15 cães adultos, distribuídos aleatoriamente em três grupos (G) com cinco animais cada, submetidos aos seguintes eventos hipotensores: GI - cloridrato de xilazina a 2%, GII - choque hipovolêmico agudo e GIII - veneno da serpente Bothrops moojeni. Os animais, avaliados durante 30 minutos após o início do evento hipotensor, foram tratados com cloridrato de ioimbina (GI), amido hidroxietílico a 6% (GII) e cetoprofeno (GIII) e reavaliados por mais 30 minutos. Somente os animais do GII apresentaram redução da PVP após o evento hipotensor e... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cão; Xilazina; Ioimbina; Choque hipovolêmico; Amido hidroxie; Tílico; Bothrops moojeni; Cetoprofeno. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352005000600006 |
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| Queiroz,MR; Mamede,CC; Fonseca,KC; Canabrava,LCMN; França,LV; Silva,MC; Stanziola,L; Beletti,ME; Canabrava,HAN; Oliveira,F. |
| A myotoxin phospholipase A2 homologue, BmooMtx, was isolated from the venom of Bothrops moojeni by a combination of ion-exchange chromatography on DEAE-Sephacel column and gel filtration on Sephadex G-75. SDS-PAGE showed the enzyme to be a monomer with a molecular weight of 16,500. BmooMtx induced release of creatine kinase and morphological analyses indicated that it provoked an intense myonecrosis, with visible leukocyte infiltrate and damaged muscle cells 24 hours after injection. Anti-BmooMTx antibodies partially neutralized the myotoxic activity of BmooMtx and crude B. moojeni venom, as judged by determination of plasma creatine kinase levels and histological evaluation of skeletal muscle in mice. Anti-BmooMTx antibodies were effective in reducing the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops moojeni; Hyperalgesia; Myotoxin; Edema. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000100007 |
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| Nascimento, Fernanda Gatti de Oliveira; Barbosa, Fernando Cristino; Rodrigues, Renata Dias; Pereira, Heloisa Castro; Gomes, Lara Reis; de Souza, Rafael Rocha. |
| Foi comparada a eficiência de duas técnicas de coloração, Ziehl-Neelsen modificado e Safranina modificada, para Cryptosporidium sp. em amostras fecais de duas espécies de Jararacas criadas em cativeiro. Cryptosporidium é um protozoário de carácter cosmopolita, oportunista, que acomete varias espécies, classificado dentro do filo Apicomplexa, e suas espécies parasitam as microvilosidades das células epiteliais do trato gastrointestinal. A localização desse protozoário caracteriza-se por ser intracelular, porém extracitoplasmático. Diferentemente de outros organismos, nos quais as infecções por Cryptosporidium são autolimitantes em indivíduos imunocompetentes, a criptosporidiose em répteis é frequentemente crônica e pode ser letal para serpentes. A... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops moojeni; Bothrops atrox; Oocistos. |
| Ano: 2014 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/23710 |
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| Benati,Rogério Bodini; Costa,Tássia Rafaela; Cacemiro,Maira da Costa; Sampaio,Suely Vilela; Castro,Fabíola Attié de; Burin,Sandra Mara. |
| Abstract Background: Chronic myeloid leukemia (CML) is a BCR-ABL1+ myeloproliferative neoplasm marked by increased myeloproliferation and presence of leukemic cells resistant to apoptosis. The current first-line therapy for CML is administration of the tyrosine kinase inhibitors imatinib mesylate, dasatinib or nilotinib. Although effective to treat CML, some patients have become resistant to this therapy, leading to disease progression and death. Thus, the discovery of new compounds to improve CML therapy is still challenging. Here we addressed whether MjTX-I, a phospholipase A2 isolated from Bothrops moojeni snake venom, affects the viability of imatinib mesylate-resistant Bcr-Abl+ cell lines. Methods: We examined the cytotoxic and pro-apoptotic effect... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chronic myeloid leukemia; Bcr-Abl; Phospholipase A2; MjTX-I; Bothrops moojeni; Apoptosis; Cytotoxicity. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100330 |
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| Silva,TB.; Rossellini,M.; Dal Pai Silva,M.; Silva,RJ.. |
| The aim of this study was to evaluate the morphology of the species Sticholecitha serpentis Prudhoe, 1949 by means of histological procedures. Helminths were previously fixed in Railliet & Henry solution, uncompressed and were included in 2-hydroxyethyl-methacrylate. Longitudinal and transverse serial sections with a 4-mum thickness were performed in a microtome (Leica RM 2165), stained with haematoxylin-eosin and then analyzed in a computerized image analysis system (Qwin Lite 2.5, Leica). Structures of systematic value, such as oral sucker, acetabulum, prepharynx, pharynx, esophagus, intestinal caeca, vitelline glands, ovary, uterus, cirrus pouch and testicles were described. Structures that were poorly visible in total preparations were also... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sticholecitha serpentis; Digenea; Bothrops moojeni; Snakes; Brazil. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000400010 |
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| Barbosa,PSF; Martins,AMC; Toyama,MH; Joazeiro,PP; Beriam,LOS; Fonteles,MC; Monteiro,HSA. |
| Snake venom proteins from the C-type lectin family have very distinct biological activities despite their highly conserved primary structure, which is homologous to the carbohydrate recognition region of true C-type lectins. We purified a lectin-like protein (BmLec) from Bothrops moojeni venom and investigated its effect on platelet aggregation, insulin secretion, antibacterial activity, and isolated kidney cells. The BmLec was purified using two chromatographic steps: affinity chromatography and reverse phase high performance liquid chromatography (HPLC). BmLec showed a dose-dependent platelet aggregation and significantly decreased the bacterial growth rate in approximately 15%. During scanning electron microscopy, the profile of Xanthomonas axonopodis... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops moojeni; Kidney; Platelet aggregation; Insulin; Antibacterial activity. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000300016 |
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| Silva,Reinaldo José da; Karasawa,Andrea Satie Matsubara; Cherubini,André Luis; Barrella,Thomaz Henrique; Lopes,Carlos Alberto de Magalhães; Amarante,Alessandro Francisco Talamini. |
| The occurrence of Crepidobothrium sp.(Cestoda, Proteocephalidae) in the intestine of Bothrops moojeni (Hoge,1965)(Serpentes, Viperidae) is reported. The host snake was rescued from the fauna in Porto Primavera dam, Mato Grosso do Sul State, Brazil. The snake died in captivity on July 13,1999. At necropsy, 28 tapeworms were found in the snake intestine. The analysis of specimens morphology allowed the conclusion that they belong to the Crepidobothrium (Monticelli, 1900) genus. It was not possible to determine the Crepidobothrium species due to the lack of the gravid proglottids. This is the first report of B. moojeni as a host of cestodes. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cestoda; Proteocephalidae; Crepidobothrium; Bothrops moojeni; Snake. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-81752001000200006 |
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| Registros recuperados: 11 | |
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